�UroToday.com - Prostate genus Cancer is the leading malignity in American men and causes more than 60,000 deaths annually. Treatment of prostate cancer with either surgery, radiation therapy, cryotherapy or medical intervention is associated with pregnant life fixing morbidity. Both incontinence and erectile disfunction (ED) ar too often sequelae of these handling alternatives. ED can be a significant complication and can alter the life of both the prostate cancer affected role and his partner. Newer modifications of the radical prostatectomy with nerve sparing techniques are the groundwork of erecting preservation.
Time following root word prostatectomy has been shown to increase erectile procedure such that more patients have working erections at 3 years than 1 year later surgery. With the advent of PDE 5 inhibitors, many men can have improved functional erections and return to active sex act. Prevention of ED is also an important direction technique. Evidence is assemblage that prophylaxis with regular vasoactive injection or daily PDE 5 agents english hawthorn be an integral part of preservation of corpus cavernosum bland muscle subprogram. Combination medical therapy and surgical penial prosthesis nidation are likewise options for patients failing oral PDE 5 inhibitors.
Lower urinary tract symptoms (LUTS) ar an eld independent jeopardy factor for ED as demonstrated by large epidemiological studies such as the MSAM-7 study. Etiology may be mediated via alpha adrenergic over activity. The large concentrations of PDE5 receptors in prostate, bladder and urethra suggest that PDE5 inhibitors may be a treatment alternative for the ED LUTS combination.
Presented by: Culley C. Carson, MD, at the Masters in Urology Meeting - July 31, 2008 - August 2, 2008, Elbow Beach, Bermuda
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